FAS

Classified Human Subjects Research Continues at DOE

08.10.18 | 2 min read | Text by Steven Aftergood

dozen classified programs that involved research on human subjects were underway last year at the Department of Energy.

Human subjects research refers broadly to the collection of scientific data from human subjects. This could involve physical procedures that are performed on the subjects, or simply interviews and other forms of interaction with them.

Little information is publicly available about the latest DOE programs, most of which have opaque, non-descriptive names such as TristanIdaho Bailiff and Moose Drool. But a list of the classified programs was released this week under the Freedom of Information Act.

Human subjects research erupted into national controversy 25 years ago with reporting by Eileen Welsome of the Albuquerque Tribune on human radiation experiments that had been conducted by the Atomic Energy Commission, many of which were performed without the consent of the subjects. A presidential advisory committee was convened to document the record and to recommend appropriate policy responses.

In 2016, the Department of Energy issued updated guidelines on human subjects research, which included a requirement to produce a listing of all classified projects involving human subjects. It is that listing that has now been released.

“Research using human subjects provides important medical and scientific benefits to individuals and to society. The need for this research does not, however, outweigh the need to protect individual rights and interests,” according to the 2016 DOE guidance on protection of human subjects in classified research.

An extravagantly horrific example of fictional human subject research was imagined by Lindsay Anderson in his 1973 film O Lucky Man! which captured the zeitgeist for a moment.

publications
See all publications
Government Capacity
Policy Memo
We Need a U.S. Permitting Corps: Executive and Legislative Recommendations

Despite significant political momentum behind reform efforts, limited attention has been paid to the federal workforce that will actually be responsible for interpreting and implementing new permitting regulations and better outcomes.

07.08.26 | 10 min read
read more
Environment
Press release
Amid Sweltering Weather, the Federation of American Scientists Releases Expert-Sourced “State and Local Heat Policy Agenda”

Nearly 150 organizations and government officials have endorsed the call to action and solutions for extreme heat, now public at HeatAgenda.US Washington, D.C. – July 7, 2026 – As millions of Americans continue to struggle to stay cool following one of the hottest Independence Day holidays on record, the Federation of American Scientists (FAS), one […]

07.07.26 | 3 min read
read more
Environment
Issue Brief
Policy Memo
The State and Local Heat Policy Agenda

Addressing rising heat will take all of us. Together, we can create heat-safe homes, workplaces, schools, childcare facilities, and communities – the backbone of a heat-ready nation.

07.07.26 | 5 min read
read more
Emerging Technology
day one project
Policy Memo
Securing Cell-Free Biomanufacturing as a Strategic National Capability

DNA synthesis and export controls remain the primary regulatory safeguards against de novo production of harmful biological agents, yet governance frameworks lack the situational awareness and enforcement capacity to keep pace with rapidly falling technical barriers.

07.02.26 | 11 min read
read more