Re-envisioning Reporting of Scientific Methods
Summary
The information contained in the methods section of the overwhelming majority of research publications is insufficient to definitively evaluate research practices, let alone reproduce the work. Publication—and subsequent reuse—of detailed scientific methodologies can save researchers time and money, and can accelerate the pace of research overall. However, there is no existing mechanism for collective action to improve reporting of scientific methods. The Biden-Harris Administration should direct research-funding agencies to support development of new standards for reporting scientific methods. These standards would (1) address ongoing challenges in scientific reproducibility, and (2) benefit our nation’s scientific enterprise by improving research quality, reliability, and efficiency.
As surrogate markers are increasingly being accepted by FDA to support approval of new drugs and biologics, it is imperative that patients and clinicians understand whether such novel endpoints are reflective of meaningful clinical benefits.
The Secretary of Health and Human Services should launch a Department-wide initiative to reduce wasteful spending on health services, drugs, and ineffective medical devices, saving many lives as well as billions of dollars annually.
Bureaucracy significantly hinders federally funded scientific research, diverting scientists’ time from discovery to low-value administrative tasks.
Mandated publication would ensure all federal grants have outputs, whether hypotheses were supported or not, reducing repetition of ideas in future grant applications.