By better harnessing the power of data, we can build a learning healthcare system where outcomes drive continuous improvement and where healthcare value leads the way.

In this unprecedented inflection point (and time of difficult disruption) for higher education, science funding, and agency structure, we have an opportunity to move beyond incremental changes and advocate for bold, new ideas that envision a future of the scientific research enterprise that looks very different from the current system.

Assigning persistent digital identifiers (Digital Object Identifiers, or DOIs) and using ORCIDs (Open Researcher and Contributor IDs) for key personnel to track outputs for research grants will improve the accountability and transparency of federal investments in research and reduce reporting burden.

Research funding agencies should apply the content of grant applications to AI tools to predict the future of scientific and technological breakthroughs, enhance peer review, and encourage better research investment decisions by both the public and the private sector.