Ambitious, Achievable, and Sustainable: A Blueprint for Reclaiming American Research Leadership
Summary
The next Administration should accelerate federal basic and applied research investments over a period of five years to return funding to its historical average as a share of GDP. While this ambitious yet achievable strategy should encompass the entire research portfolio, it should particularly seek to reverse the long-term erosion of collective investments in physical and computer science, mathematics, and engineering to lay the foundation for economic competitiveness deep into the 21st century. This proposal outlines a strategy and series of steps for the federal government to take to reinvigorate U.S. competitiveness by restoring research and development investments.
As surrogate markers are increasingly being accepted by FDA to support approval of new drugs and biologics, it is imperative that patients and clinicians understand whether such novel endpoints are reflective of meaningful clinical benefits.
The Secretary of Health and Human Services should launch a Department-wide initiative to reduce wasteful spending on health services, drugs, and ineffective medical devices, saving many lives as well as billions of dollars annually.
Bureaucracy significantly hinders federally funded scientific research, diverting scientists’ time from discovery to low-value administrative tasks.
Mandated publication would ensure all federal grants have outputs, whether hypotheses were supported or not, reducing repetition of ideas in future grant applications.